Our Promise to you:
Premier global microbiological solutions, extensive collection of products.
24x7 CUSTOMER SERVICE
CONTACT US TO ORDER
Melanoma, also known as malignant melanoma, is the rarest and most severe type of skin cancer. It develops from the melanocytes, which are the cells in your skin that produce melanin. Melanomas are usually caused by genetic mutations resulting from exposure to ultraviolet (UV) rays from the sun. We know genetics also plays a role.
As a form of molecular medicine, targeted therapy is a drug that blocks the growth of cancer by interfering with specific molecules involved in tumor growth. It is different to non-specific treatments like chemotherapy that simply attack all rapidly dividing cells indiscriminately. Targeted drugs disrupt specific molecules to treat melanomas that have certain gene mutations. Targeted drugs can shrink or control the growth of tumors in some people and help some people live longer.
|Target||Types||Agent||Manufacturer||Start Marketing Date|
|IL2RA, IL2RB, IL2RG||Peptide immunopotentiator||Proleukin||CHIRON||1992|
|BRAF, MEK||Small molecule||Tafinlar||GSK||2013|
In the field of cancer treatment, it was observed that the bacteria have the ability to deliver tumor-specific anticancer genes and the potential tumor-targeting antitumor capability.
Creative Biogene provides a "one-stop shop" tailored to your gene research needs. We have expertise in gene knockout, knock-in/replacement and site-directed mutagenesis. Creative Biogene is able to provide you the comprehensive oncolytic bacteria genome editing service, including traditional recombineering system, CRISPR/Cas 9 system and site-specific recombination system. Simply let us know how you want the genome to be edited. We will propose the best strategy for you.
1. Yuan, M., Huang, L., Chen, J. et al. The emerging treatment landscape of targeted therapy in non-small-cell lung cancer. Sig Transduct Target Ther 4, 61 (2019).
2. Torres W, Lameda V, Olivar LC, Navarro C, Fuenmayor J, Pérez A, Mindiola A, Rojas M, Martínez MS, Velasco M, Rojas J, Bermudez V. Bacteria in cancer therapy: beyond immunostimulation. J Cancer Metastasis Treat 2018;4:4.