Creative Biogene is a leading company offering high-quality filamentous fungi gene expression service for our esteemed clients around the world across both academic institutions and biotech/pharmaceutical industries. With our strong technical force, unparalleled customized service and fast delivery time, Creative Biogene specializes in providing more cost-effective gene expression service to accelerate the global research in microbial enzymes.
Filamentous fungi have found application in many technologies which include the production of antibiotics, commercial enzymes and organic compounds. Fungal-based systems combine the advantages of a microbial system such as a simple fermentability with the excellent capability of secreting proteins that are modified according to a general eukaryotic scheme1. Furthermore, Due to the superior capacities of high-level secretion and decomposer lifestyle, filamentous fungi become the vehicle of choice. Many industrial strains of fungi which have been classified GRAS, can grow on relatively inexpensive culture, and can both produce and secrete very high levels of microbial enzymes. However, filamentous fungi have some disadvantages, such as the complexity and relative dearth of understanding the physiology. Our talented scientists have extensive experience to help you solve all your problems.
Fig.1 General scheme of secretion pathway for heterologous protein production (Sharma, et al. 2009)
As a leader in gene expression service, Creative Biogene provides a "one-stop shop" tailored to your microbial enzymes research needs. Our services range from sequence optimization and synthesis, plasmid construction, induce, flexible scale microbial enzymes purification and characterization, post processing of purified protein et al. It's entirely customizable and flexible to fit how you run projects. Our vision is to provide superior and affordable filamentous fungi gene expression service to the academic and industrial scientific research communities.
Workflow of filamentous fungi gene expression service
Advantages of filamentous fungi gene expression system
• High-level of expression
• Low cost
• Generally regarded as safe
As state-of-the-art microbial enzymes solutions provider, Creative Biogene has a proprietary technology platform and an international network to provide our clients with professional and comprehensive solutions and applications. Creative Biogene specialize in filamentous fungi gene expression system. Simply let us know the gene to be expressed. We will propose the best strategy tailored to your requirements.
1. Sharma, R., Katoch, M., Srivastava, P. S., & Qazi, G. N. (2009). Approaches for refining heterologous protein production in filamentous fungi. World Journal of Microbiology & Biotechnology, 25(12), 2083-2094.