Creative Biogene has accumulated extensive and further experience in manufacturing microbial biomass and offers dedicated services for in-house or partnered microbial fermentation of live microorganisms.
Probiotics are a group of microorganisms that impart great health benefit to human through altering the gut microflora. Lactobacilli, Bifidobacterium, Bacilli, and yeasts are belonged to the probiotics.
Creative Biogene can help you with commercial probiotics biomanufacturing and packaging in different dosage forms, including capsules, tablets, powders and liquids. Fermented foods contain specific probiotic strains at a suitable level and thus have antioxidant properties, immunomodulatory, antithrombic, and antihypertensive properties. We can also provide custom fermentation services to improve food taste, flavor, nutrients through utilizing specific probiotics.
Live biotherapeutic products are defined as live microbes that could be used to prevent, treat, or curve a disease or disorders in human.
• Fermentation-derived Microbes Used for Treating Solid Tumors
Mcrobiosci's experience in producing live biotherapeutic microbes includes but is not limited to strain optimization, process development, scale-up, formulation, and packaging. Our capability and expertise in development and production of live anti-tumor microbes make us the best choice for cost effective fermentation services. Solid tumors possess abnormal blood vessel structure and thus provide a suitable habitat for anaerobic bacteria colonization. A series of engineered anaerobic microorganisms have been used to treat the solid tumors, including Bifidobacterium, Clostridium, Salmonella, and Escherichia.
• Probiotics with Live Biotherapeutic Products Properties
Some probiotics are accepted as live biotherapeutic products (LBPs) and have entered preclinical or clinical experiments. Genetic engineering technology has been applied to enable the living bacteria survive and colonize in human gut. We can follow you with biotherapeutic probiotics manufacturing from stage development up to and including commercial supplies.
Many live soil microorganisms such as Bacilli, Clostridium and Azotobacter have been developed well to serve as biofertilizers, biopesticide or biocontrol. They are superior to chemical pesticide in agriculture industry and are cost-effective and eco-friendly.
Creative Biogene is one of the front-runners and a recognized partner for the process development and manufacturing of live soil microorganisms. If you have any requirement for related fermentation, don't hesitate to call us or send us an E-mail.
Fermentation is usually accepted as the metabolic process that microorganisms convert sugars into our desired products. Apart from these metabolite products, the live microbes are also appealing people's interest and take an important part in global market.
Creative Biogene provides "one-stop shop" microbial fermentation services tailored to your specific application and commercial needs. We have extensive experience in probiotics fermentation with a ‘know-how' and trouble shotting capabilities to provide comprehensive probiotics manufacturing services. From genetic engineering to downstream process, we are willing to take part in your interesting project and help you at every step of your workflow.
1. Charbonneau, M. R. , Isabella, V. M. , Li, N. , & Kurtz, C. B. . (2020). 'Developing a new class of engineered live bacterial therapeutics to treat human diseases.' Nature Communications, 11(1).
2. CAnandharaj, M. , Rani, R. P. , & Swain, M. R. . (2017). 'Production of High‐Quality Probiotics by Fermentation.' Microbial Functional Foods and Nutraceuticals. John Wiley & Sons, Ltd.