Microorganisms that form biofilms generally include bacteria, fungi, and protists. And more than 80% of bacteria in nature take the form of biofilm. During an industrial activity, the metabolism of biofilm can corrode the surface of equipment and pipelines. Meanwhile, bacteria and their spores embedded in the biofilm can also spread outward and eventually become the source of contamination. Aeromonas hydrophila, Escherichia coli, Listeria and Staphylococcus are all commonly seen microbes in biofilm contaminations. With the protection of a slimy extracellular matrix that is composed of extracellular polymeric substances (EPS), the biofilm community constitutes a highly effective defense barrier to the outside environment. Such resistance is not only to physical conditions but also to antiseptics, detergents, and antibiotics, which can be 10 ~ 1000 times stronger than the planktonic counterparts. Biofilm can be a hazard in multiple areas including biopharmaceutical industries, food industries, healthcare, and medical devices. Due to its vast existence and evident or potential hazard, the control and removal of biofilms appear to be quite necessary.
With the maturation and changing of biofilms over time, the removal of the biofilm becomes increasingly difficult. Biofilms become even more resistant to the outside environment because the gathering of different types of microbes provides a larger gene pool for the secretion of more components and make up a more complicated structure for a hydrated matrix that enclosing the microbes.
Based on comprehensive and advanced biofilm testing services along with the evaluation of the system or equipment, Creative Biogene provides safe, effective and customized solutions varied from physical, biological to chemical approaches to control and remove biofilms. Each system or equipment is unique, so it is always necessary to evaluate them to determine what is present and what approach should take. Combined a great knowledge and years of experience of practicing, we can help you remove both biofilm accumulations and bioburden that are migrating within the systems and equipment with industry-leading inhibition spectrum and barely any residuals.
Effective removal of biofilms typically requires a series of cleaning and disinfection steps:
Cleaning: Cleaning is the operation whereby the visible or invisible fouling on a surface is eliminated, preventing the accumulation of residues that can enhance microorganism growth. Follow with a thorough rinse using water or other suitable liquids.
Disinfection: Use physical, chemical or biological means to totally eliminate pathogens and to reduce the number of microorganisms present to a safe level. The proper approach to use for biofilm removal will depend on the target system. Biofilm will be dissolved effectively under an extended exposure time with suitable agents. Then a final rinse is required.
Inspection: Use detection methods to confirm that the biofilm has been successfully eliminated.
We recommend you sanitize your system frequently and thoroughly to prevent biofilm from forming. If there is any need of yours, do not hesitate to contact us.